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Pharmacological Regulation of Tumor Hypoxia in Model Murine Tumors and Spontaneous Canine Tumors.

Martin BenejJinghai WuMcKenzie KreamerMartin KerySergio Corrales-GuerreroIoanna PapandreouTerence M WilliamsZihai LiEdward E GravesLaura Elizabeth SelmicNicholas C Denko
Published in: Cancers (2021)
In both transplanted murine tumors and spontaneous canine tumors we found that decreasing mitochondrial metabolism can decrease tumor hypoxia, potentially offering a therapeutic advantage.
Keyphrases
  • endothelial cells