Pharmacological Regulation of Tumor Hypoxia in Model Murine Tumors and Spontaneous Canine Tumors.
Martin BenejJinghai WuMcKenzie KreamerMartin KerySergio Corrales-GuerreroIoanna PapandreouTerence M WilliamsZihai LiEdward E GravesLaura Elizabeth SelmicNicholas C DenkoPublished in: Cancers (2021)
In both transplanted murine tumors and spontaneous canine tumors we found that decreasing mitochondrial metabolism can decrease tumor hypoxia, potentially offering a therapeutic advantage.
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