Utilization of Transcriptomic Profiling to Identify Molecular Markers Predicting Successful Recovery Following Endoscopic Sinus Surgery for Chronic Rhinosinusitis.
Axel Eluid RenteriaAnastasios ManiakasAudrey PelletierAli Filali-MouhimEmmanuelle BrochieroFabiana C P ValeraDamien AdamLeandra Endam MfunaMartin Y DesrosiersPublished in: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery (2023)
Successful recovery from ESS involves restoration of epithelial function and regulated activation of Type 1 inflammation. Excessively elevated Type 1 inflammation is associated with epithelial barrier dysfunction.