Anti-inflammatory and antinociceptive effects of sitagliptin in animal models and possible mechanisms involved in the antinociceptive activity.

Valiollah Hajhashemi Hossein Sadeghi Fatemeh Karimi Madab

Published in: The Korean journal of pain (2023)

pathways play an important role in the antinociceptive effect of sitagliptin. Additionally significant anti-inflammatory effects observed in the carrageenan test might contribute in reduction of pain response in the second phase of the formalin test.

Keyphrases

anti inflammatory
chronic pain
pain management
neuropathic pain
spinal cord