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Anticholinergic burden measures, symptoms, and fall-associated risk in older adults with polypharmacy: Development and validation of a prognostic model.

Truc Sophia DinhAndreas D MeidHenrik RudolfMaria-Sophie BrueckleAna I González-GonzálezVeronika BenchevaMatthias GogolinKym I E SnellPetra J M EldersPetra A ThuermannNorbert Donner-BanzhoffJeanet W BlomMarjan van den AkkerFerdinand M GerlachSebastian HarderUlrich ThiemPaul P GlasziouWalter Emil HaefeliChristiane Muth
Published in: PloS one (2023)
The ability of anticholinergic burden measures to predict falls does not appear to differ significantly, and the added value they contribute to risk classification in fall-prediction models is limited. Previous falls and dizziness / vertigo contributed most to model performance.
Keyphrases
  • community dwelling
  • machine learning
  • deep learning
  • physical activity
  • emergency department
  • middle aged
  • electronic health record