Exploring causal correlations between inflammatory cytokines and intervertebral disc degeneration: A Mendelian randomization.

Tao XuGuangzi ChenJian LiYingchi Zhang

Published in: JOR spine (2024)

Our MR analyses found a potential causal relationship between six inflammation cytokines (IFN-γ, IL-1b, IL-4, IL-18, SDF1a, and GCSF) and altered IVDD risk.

Keyphrases

oxidative stress
immune response
dendritic cells
risk assessment
climate change