Association of Cardiovascular Disease Risk Factors with Late Cardiotoxicity and Survival in HER2-positive Breast Cancer Survivors.

Xuexin HeJiali JiXiaolan DaiAiham Z QdaisatFrancisco J EstevaGabriel N Hortobagyi Sai-Ching Jim Yeung

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)

Hypertension and CAD history were independent prognostic factors for late severe CV events. Adding anti-HER2 agents to anthracycline-containing regimens did not substantially increase the risk for late severe cardiotoxicity and conferred better overall survival.

Keyphrases

prognostic factors
cardiovascular disease
risk factors
early onset
blood pressure
coronary artery disease
type diabetes
metabolic syndrome
cardiovascular events