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Exome sequencing-based identification of novel type 2 diabetes risk allele loci in the Qatari population.

Sarah L O'BeirneJacqueline SalitJuan L Rodriguez-FloresMichelle R StaudtCharbel Abi KhalilKhalid A FakhroAmal RobayMonica D RamstetterJoel A MalekMahmoud ZirieAmin JayyousiRamin BadiiAjayeb Al-Nabet Al-MarriAbdulbari BenerMai MahmoudMaria J ChiuchioloAlya Al-ShakakiOmar ChidiacDora StadlerJason G MezeyRonald G Crystal
Published in: PloS one (2018)
The observation that genes not previously linked to T2D in prior studies of European and Asian populations are associated with T2D in Qatar provides new insights into the complexity of T2D pathogenesis and emphasizes the importance of understudied populations when assessing genetic variation in the pathogenesis of common disorders.
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