Is SARS-CoV-2-induced disease a decisive factor influencing testosterone in males? Findings from a case-control ex post facto study.

Paolo CapogrossoAlessandro BertiniMarina PontilloAnna Maria FerraraAlice CotelessaCristina CarenziGiuseppe A RamirezCristina TresoldiMassimo LocatelliAntonella CastagnaFrancesco De CobelliMoreno TresoldiAlberto ZangrilloGiovanni LandoniPatrizia Rovere-QueriniFabio CiceriFrancesco MontorsiGiacomo MontiAlessia d'Arma

Published in: Andrology (2023)

This case-control ex post facto study showed lower tT levels in men with COVID-19 compared to those without COVID-19 despite both groups have been equally admitted to ICU for severe ARDS, thus suggesting a possible direct impact of SARS-CoV-2 infection toward circulating tT levels and a consequent more severe clinical outcome.

Keyphrases

sars cov
case control
coronavirus disease
respiratory syndrome coronavirus
intensive care unit
early onset
mechanical ventilation
acute respiratory distress syndrome
oxidative stress
extracorporeal membrane oxygenation
high glucose
endothelial cells