Peripheral blood mononuclear cell activation sustains seizure activity.

Laura Librizzi Diogo Vila Verde Francesca Colciaghi Francesca AnzellottiMaria Cristina RegondiMassimo CostanzaBarbara CipellettiMarco de Curtis

Published in: Epilepsia (2021)

Activated peripheral immune cells, such as PBMCs, and the extravasation of serum proteins in a condition of BBB impairment contribute to seizure generation.

Keyphrases

peripheral blood
temporal lobe epilepsy
single cell
blood brain barrier
cell therapy
stem cells
mesenchymal stem cells
bone marrow