Identifying and modulating distinct tremor states through peripheral nerve stimulation in Parkinsonian rest tremor.
Beatriz S ArrudaCarolina ReisJames J SermonAlek PogosyanPeter BrownHayriye CagnanPublished in: Journal of neuroengineering and rehabilitation (2021)
These results highlight that phase-locked peripheral nerve stimulation has the potential to reduce tremor. However, there can be multiple independent tremor oscillation patterns even within the same limb. Parameters of peripheral stimulation such as stimulation phase may need to be adjusted continuously in order to sustain systematic suppression of tremor amplitude.