Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes.

Julia A Zakashansky Amanda Hikari ImamuraDarwin F SalgadoHeather C Romero MerciecaRaphael F L AguasAngelou M LaoJoseph PariserNetzahualcóyotl Arroyo-Currás Michelle Khine

Published in: Analytical methods : advancing methods and applications (2021)

Using the children's toy, Shrinky-Dink©, we present an aptamer-based electrochemical (E-AB) assay that recognizes the spike protein of SARS-CoV-2 in saliva for viral infection detection. The low-cost electrodes are implementable at population scale and demonstrate detection down to 1 ag mL-1 of the S1 subunit of the spike protein.

Keyphrases

sars cov
label free
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loop mediated isothermal amplification
protein protein
gold nanoparticles
real time pcr
binding protein
young adults
reduced graphene oxide
quantum dots
small molecule
solid state
highly efficient
molecularly imprinted