Altered Functional Connectivity Density in Young Survivors of Acute Lymphoblastic Leukemia Using Resting-State fMRI.
Linglong ChenYaru ZhanFei HeShouhua ZhangLin WuHonghan GongFuqing ZhouXianjun ZengHai-Bo XuPublished in: Cancer management and research (2020)
Our results suggest the altered functional connectivity of young survivors of ALL in the posterior region of the brain and posterior lobe of the cerebellum. Alterations in spontaneous neuronal activity seem to parallel the neurocognitive testing, which indicates that the rs-fMRI could be used as a neuroimaging marker for neurological impairment in ALL patients.
Keyphrases
- resting state
- functional connectivity
- acute lymphoblastic leukemia
- end stage renal disease
- young adults
- newly diagnosed
- ejection fraction
- prognostic factors
- middle aged
- bipolar disorder
- allogeneic hematopoietic stem cell transplantation
- patient reported outcomes
- brain injury
- acute myeloid leukemia
- subarachnoid hemorrhage
- blood brain barrier