Therapeutic drug monitoring of gabapentin in various indications.
Margrete Larsen BurnsEinar KingeMimi Stokke OpdalSvein I JohannessenCecilie Johannessen LandmarkPublished in: Acta neurologica Scandinavica (2019)
Due to extensive pharmacokinetic variability, TDM can benefit patients using gabapentin. Challenges with applying TDM in new indications such as RLS include different dosage regimens and consequently different interpretation of serum concentrations. Thus, TDM should be requested on clear clinical grounds and the service tailored according to the therapeutic indication.