ERK1/2-Dependent Inhibition of Glycolysis in Curcumin-Induced Cytotoxicity of Prostate Carcinoma Cells.

Published in: BioMed research international (2022)

Taken together, the results provide mechanistic evidence for the antiglycolytic and cytotoxic roles of curcumin through inhibition of the MEK/ERK signaling pathway in prostate carcinoma cells preadapted to acidic conditions.

Keyphrases

signaling pathway
pi k akt
prostate cancer
benign prostatic hyperplasia
cell proliferation
epithelial mesenchymal transition
induced apoptosis
diabetic rats
high glucose
ionic liquid
endoplasmic reticulum stress