Long-term survival of full-thickness corneal xenografts from α1,3-galactosyltransferase gene-knockout miniature pigs in non-human primates.

Chang Ho Yoon Se-Hyun Choi Hyuk Jin Choi Hyun Ju Lee Hee-Jung Kang Jong Min Kim Chung-Gyu Park Ki Myung Choi Hyunil Kim Curie Ahn Mee-Kum Kim

Published in: Xenotransplantation (2019)

The GTKOm pig corneal graft achieved long-term survival when combined with anti-CD20 antibody treatment. Inhibition of activated B cells and complement is imperative even when using GTKO pig corneas.

Keyphrases

optical coherence tomography
endothelial cells
wound healing
copy number
genome wide
induced pluripotent stem cells
cataract surgery
gene expression
transcription factor