Platelet-derived growth factor predicts prolonged relapse-free period in multiple sclerosis.

Mario Stampanoni BassiEnnio IezziGirolama A MarfiaIlaria SimonelliAlessandra MusellaGeorgia MandolesiDiego FresegnaPatrizio PasqualettiRoberto FurlanAnnamaria FinardiGiorgia MataluniDoriana LandiLuana GilioDiego CentonzeFabio Buttari

Published in: Journal of neuroinflammation (2018)

Our results suggest that PDGF could promote a more prolonged relapse-free period during the course of RR-MS, without influencing inflammation reactivation and inflammation-driven neuronal damage and likely enhancing adaptive plasticity.

Keyphrases

growth factor
multiple sclerosis
oxidative stress
free survival
mass spectrometry
ms ms
white matter
smooth muscle
vascular smooth muscle cells
brain injury
blood brain barrier