Development and Quality Control of a Population Pharmacokinetic Model Library for Caspofungin.
Nuo XuYufei ShiYixue WangWen Yao MakWenyu YangKar Weng NgYue WuZhijia TangQingfeng HeGangfeng YanXiao-Qiang XiangXiao ZhuPublished in: Pharmaceutics (2024)
At the recommended dosage, adult patients showed notably lower exposure to caspofungin compared to pediatric patients. Considering body size, liver function, and serum albumin is crucial when determining caspofungin dosage regimens. Furthermore, further research is required to comprehensively understand the pharmacokinetics of caspofungin in pediatric patients.
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