Sex Hormones as Key Modulators of the Immune Response in Multiple Sclerosis: A Review.

Federica MurgiaFlorianna GiagnoniLorena LoreficePaola CariaTinuccia DettoriMaurizio Nicola D'alterio Stefano AngioniAran J HendrenPierluigi Caboni Monica PibiriGiovanni MonniEleonora CoccoLuigi Atzori

Published in: Biomedicines (2022)

A correlation has been identified between sex hormones and MS clinical activity. The combination of disease-modifying therapies with estrogen or estrogen plus a progestin receptor modulator promoting myelin repair might represent an important strategy for MS treatment in the future.

Keyphrases

multiple sclerosis
immune response
white matter
mass spectrometry
estrogen receptor
ms ms
small molecule
current status
binding protein
combination therapy
inflammatory response