Synergistic use of anti-inflammatory ketorolac and gentamicin to target staphylococcal biofilms.
Amita SekarDmitry GilPeyton TierneyMadeline McCanneVikram DaesetyDarina TrendafilovaOrhun K MuratogluEbru OralPublished in: Journal of translational medicine (2024)
The results of this study have a significant impact on the local administration of antibiotics and other therapeutic agents commonly used in the prevention and treatment of orthopaedic infections. Further, these results warrant the study of synergy for the concurrent or sequential administration of non-antibiotic drugs for antimicrobial effect.