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The mechanism of human neural stem cell secretomes improves neuropathic pain and locomotor function in spinal cord injury rat models: through antioxidant, anti-inflammatory, anti-matrix degradation, and neurotrophic activities.

I Nyoman SemitaDwikora Novembri UtomoHeri SurotoI Ketut SudianaParama Gandi
Published in: The Korean journal of pain (2022)
The present study demonstrated the mechanism of HNSC-secretome in improving neuropathic pain and locomotor function in SCI through antioxidant, anti-inflammatory, anti-matrix degradation, and neurotrophic activities.
Keyphrases
  • neuropathic pain
  • spinal cord injury
  • anti inflammatory
  • spinal cord
  • stem cells
  • endothelial cells
  • oxidative stress
  • induced pluripotent stem cells
  • bone marrow