Activation of miR-500a-3p/CDK6 axis suppresses aerobic glycolysis and colorectal cancer progression.
Yu LiuWentao TangLi RenTianyu LiuMeng YangYe WeiYijiao ChenMeiling JiGuosong ChenWenju ChangJianmin XuPublished in: Journal of translational medicine (2022)
Our study revealed a potential tumor-suppressive role of miR-500a-3p in CRC, specifically targeting CDK6 and inhibiting cancer cell proliferation and aerobic glycolysis, which may provide new insights into novel prognostic biomarkers and therapeutic targets for CRC.