Effects of thiostrepton alone or in combination with selumetinib on triple-negative breast cancer metastasis.

Funda Demirtas Korkmaz Irem Dogan Turacli Guldal EsendagliAbdullah Ekmekci

Published in: Molecular biology reports (2022)

This study suggests that inhibiting FoxM1 as a single target is more effective than combined treatment with MEK in theTNBC allograft model. The therapeutic efficacy of THIO should be investigated with further studies on appropriate drug delivery systems.

Keyphrases

pi k akt
replacement therapy