Decreased pain sensitivity and alterations of cerebrospinal fluid and plasma inflammatory mediators after total hip arthroplasty in patients with disabling osteoarthritis.

Martin F BjurströmMikael BodelssonMichael R IrwinCamilla OrbjörnOskar HanssonNiklas Mattsson-Carlgren

Published in: Pain practice : the official journal of World Institute of Pain (2021)

THA leads to long-term decreases in pain sensitivity, indicative of resolution of sensitization processes. Changes in CSF and plasma levels of IP-10, and plasma IL-8, may be associated with altered pain phenotype.

Keyphrases

chronic pain
pain management
cerebrospinal fluid
neuropathic pain
total hip arthroplasty
oxidative stress
spinal cord
knee osteoarthritis