Striatal ZBTB16 Is Associated With Cognitive Deficits in Alzheimer Disease Mice.

Sangjoon LeeTae Kyoo KimJi Eun ChoiHye-Sun KimHeh-In Im

Published in: International neurourology journal (2022)

This study demonstrates that perturbation of transcriptional regulation of ZBTB16 during pathological aging may influence cognitive impairments and reveals a potent approach to targeting the transcriptional regulation of the striatum for the treatment of AD.

Keyphrases

mild cognitive impairment
parkinson disease
functional connectivity
cancer therapy
high fat diet induced
metabolic syndrome
drug delivery
combination therapy
insulin resistance
smoking cessation