Alzheimer's genetic risk is reduced in primary age-related tauopathy: a potential model of resistance?

Corey T McMillanEdward B LeeKyra Jefferson-GeorgeAdam NajVivianna M Van DeerlinJohn Q TrojanowskiDavid A Wolk

Published in: Annals of clinical and translational neurology (2018)

The presence of genotypic differences between PART and AD suggest that PART can provide a genetic model of NFT risk and potential Aβ resistance to inform disease-modifying therapies.

Keyphrases

genome wide
cognitive decline
dna methylation