Extensive genetic diversity of Plasmodium vivax dbp-II in Rio de Janeiro Atlantic Forest and Brazilian Amazon Basin: evidence of positive selection.
Natália Ketrin Almeida-de-OliveiraLidiane Lima-CuryRebecca de Abreu-FernandesAline de Rosa LavigneAnielle de Pina-CostaDaiana de Souza Perce-da-SilvaMarcos CatanhoPatrícia BrasilCláudio Tadeu Daniel-RibeiroMaria de Fátima Ferreira-da-CruzPublished in: Malaria journal (2020)
The results highlight that the pvdbp-II polymorphisms are positively selected by host's immune pressure. The characterization of pvdbp-II polymorphisms might be useful for designing effective DBP-II-based vaccines.
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