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Sex-dependent effects of chronic intermittent voluntary alcohol consumption on attentional, not motivational, measures during probabilistic learning and reversal.

Claudia G AguirreAlexandra StolyarovaKanak DasSaisriya KolliVincent MartyLara RayIgor SpigelmanJuan Luis Romero Sosa
Published in: PloS one (2020)
Females exhibit increased vulnerability to EtOH effects in early learning: there were sex-dependent EtOH effects on attentional measures during pretraining and discrimination phases. We also found sex-independent EtOH effects on exploration strategies during reversal. Future studies should aim to uncover the neural mechanisms for changes in attention and exploration in both acute and prolonged EtOH withdrawal.
Keyphrases
  • alcohol consumption
  • working memory
  • liver failure
  • climate change
  • drug induced
  • hepatitis b virus