Sex-dependent effects of chronic intermittent voluntary alcohol consumption on attentional, not motivational, measures during probabilistic learning and reversal.
Claudia G AguirreAlexandra StolyarovaKanak DasSaisriya KolliVincent MartyLara RayIgor SpigelmanJuan Luis Romero SosaPublished in: PloS one (2020)
Females exhibit increased vulnerability to EtOH effects in early learning: there were sex-dependent EtOH effects on attentional measures during pretraining and discrimination phases. We also found sex-independent EtOH effects on exploration strategies during reversal. Future studies should aim to uncover the neural mechanisms for changes in attention and exploration in both acute and prolonged EtOH withdrawal.