Association of IGF-1 and IGF-2 genotypes with respiratory muscle strength in individuals with COPD: A cross-sectional study.
Giovanna de CarvalhoWalter Sepúlveda LoyolaLuana Oliveira de LimaStheace Kelly Fernandes SzezerbatyRegina Célia PoliHector Gutierrez-EspinozaJuan José Valenzuela-FuenzalidaVanessa Suziane ProbstPublished in: Medwave (2024)
The polymorphisms of IGF-1 and IGF-2 displayed stronger correlations with respiratory muscle strength compared to blood biomarkers in patients with chronic obstructive pulmonary disease. Specific genotypes of IGF-1 and IGF-2 were associated with reduced respiratory muscle strength in this population.