The interaction effects between TLR4 and MMP9 gene polymorphisms contribute to aortic aneurysm risk in a Chinese Han population.

Tan LiXu ZhangLiang SangXin-Tong LiHai-Yang SunJun YangYingxian Sun

Published in: BMC cardiovascular disorders (2019)

The novel interaction between TLR4rs1927914 and MMP9rs17576 polymorphisms could increase the risk of AA disease or its subtypes by exerting epistatic and cumulative effects.

Keyphrases

toll like receptor
aortic aneurysm
inflammatory response
immune response
nuclear factor