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Mutant RAS-driven Secretome Causes Skeletal Muscle Defects in Breast Cancer.

Ruizhong WangAditi S KhatpeBrijesh KumarHenry Elmer MangKatie BaticAdedeji K AdebayoHarikrishna Nakshatri
Published in: Cancer research communications (2024)
Mutant RAS- and PIK3CA-driven breast cancers distinctly affect the function of skeletal muscle. Therefore, research and therapeutic targeting of cancer-induced systemic effects need to take aberrant cancer genome into consideration.
Keyphrases
  • skeletal muscle
  • wild type
  • papillary thyroid
  • squamous cell
  • insulin resistance
  • drug induced
  • cancer therapy
  • high glucose
  • genome wide
  • oxidative stress
  • drug delivery
  • dna methylation
  • endothelial cells
  • stress induced