LncRNA-mRNA expression profile and functional network of vascular dysfunction in septic rats.

Ye-Chen HanZhu-Jun ShenYi-Ning WangRuo-Lan XiangHong-Zhi Xie

Published in: European journal of medical research (2023)

We determined the differentially expressed lncRNAs and mRNAs in the aorta of septic rats using microarrays. Further studies on these lncRNAs will help elucidate the mechanism of sepsis at the genetic level and may identify potential therapeutic targets.

Keyphrases

acute kidney injury
network analysis
genome wide analysis
intensive care unit
oxidative stress
pulmonary artery
genome wide
septic shock
copy number
gene expression
coronary artery
pulmonary hypertension