Xidaosterols A and B, two new steroids with unusual α-keto-enol functionality from the South China Sea sponge Neopetrosia chaliniformis.

Two new C29 steroids, xidaosterols A (1) and B (2), characterised by a common unusual α-keto-enol functionality bearing A-ring, together with three related known ones (3-5), were isolated from the South China Sea sponge Neopetrosia chaliniformis. Their structures were elucidated by extensive spectroscopic analyses and comparison with the spectral data reported in the literature, Xidaosterol B is an A-nor derivative of 1.