Impact of concomitant fibrates on immunotherapy outcomes for advanced non-small cell lung cancer.

William A StokesMadhusmita BeheraRenjian JiangDavid A GutmanZhonglu HuangAbigail BurnsNikhil T SebastianVidula SukhatmeMichael C LoweSuresh S RamalingamVikas P SukhatmeDrew Moghanaki

Published in: Cancer medicine (2022)

Concomitant fibrates are associated with improved OS among NSCLC patients receiving ICI but not among those receiving chemotherapy. This hypothesis-generating observation supports a potential role for fibrates as an adjunct to immunotherapy.

Keyphrases

advanced non small cell lung cancer
epidermal growth factor receptor
small cell lung cancer
tyrosine kinase
type diabetes
radiation therapy
metabolic syndrome
skeletal muscle
weight loss
rectal cancer