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Single-Cell RNA Sequencing Identifies Crucial Genes Influencing the Polarization of Tumor-Associated Macrophages in Liver Cancer.

Kedong XuMingyi DongZhengqiang WuLinfei LuoFei XieFan LiHongyan HuangFenfen WangXiaofeng XiongZhili Wen
Published in: International journal of genomics (2024)
Our findings suggest the PRDM1 gene is a key regulator of M2 macrophage polarization, contributing to the immunosuppressive TME in HCC.
Keyphrases
  • single cell
  • genome wide
  • rna seq
  • genome wide identification
  • dna methylation
  • transcription factor
  • copy number
  • high throughput
  • genome wide analysis
  • gene expression
  • bioinformatics analysis