Qualitative and quantitative cytomorphological features of primary anaplastic lymphoma kinase-positive lung cancer.

Ryuko TsukamotoHiroyuki OhsakiSho HosokawaYasunori TokuharaShingo KamoshidaToshiko SakumaTomoo ItohChiho Ohbayashi

Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2019)

These results show that the cytomorphological features of signet ring cells, nuclear grooves and nucleoli shape can help to triage a small amount of cytological and biopsy specimens for appropriate molecular testing of primary ALK (+) lung cancer.

Keyphrases

fine needle aspiration
induced apoptosis
emergency department
cell cycle arrest
systematic review
high resolution
advanced non small cell lung cancer
cell death
cell proliferation
endoplasmic reticulum stress
pi k akt