Relation between sex hormones and leucocyte telomere length in men with idiopathic pulmonary fibrosis.
Chuling FangHui HuangQian ZhangNa WangXiaoyan JingJian GuoMartin FeriancZuojun XuPublished in: Respirology (Carlton, Vic.) (2020)
Plasma testosterone is associated with LTL independent of age or rare protein-altering variants of telomerase. No genetic variations of androgen-related pathway genes are associated with androgen concentrations. Further studies are warranted to examine whether hormonal interventions might retard telomere loss in male IPF patients.
Keyphrases
- idiopathic pulmonary fibrosis
- end stage renal disease
- genome wide
- ejection fraction
- newly diagnosed
- chronic kidney disease
- interstitial lung disease
- copy number
- physical activity
- peritoneal dialysis
- prognostic factors
- type diabetes
- gene expression
- patient reported outcomes
- adipose tissue
- metabolic syndrome
- skeletal muscle
- polycystic ovary syndrome
- replacement therapy
- genome wide analysis
- genome wide identification