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Does adding hydrogen peroxide to chlorhexidine gluconate increase the effectiveness of skin preparation in reducing cutaneous Cutibacterium levels? A randomized controlled trial.

William L CrutcherJoshua C AcideraAnastasia J WhitsonFrederick A MatsenJason E Hsu
Published in: Journal of shoulder and elbow surgery (2024)
In this randomized controlled study, there was no additional benefit of using hydrogen peroxide as an adjunct to chlorhexidine gluconate skin preparation in the reduction of cutaneous Cutibacterium levels. Neither preparation was able to eliminate repopulation of Cutibacterium on the skin surface from the dermal sebaceous glands.
Keyphrases
  • hydrogen peroxide
  • wound healing
  • nitric oxide
  • soft tissue
  • molecularly imprinted
  • systematic review
  • double blind
  • open label
  • clinical trial
  • placebo controlled
  • mass spectrometry
  • study protocol