cis-Platinum Complex Encapsulated in Self-Assembling Cyclic Peptide Dimers.
Nuria Rodríguez-VázquezRebeca García-FandiñoMaría J AldegundeJosé BreaMaría Isabel LozaManuel AmorínJuan R GranjaPublished in: Organic letters (2017)
A new cyclic peptide dimer that encapsulates cisplatin complexes in its internal cavity is described. The resulting complex showed cytotoxic activity at A2780 ovarian cancer cell lines independent of acquired platinum resistance.
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