Poor Cognitive Agility Conservation in Obese Aging People.
Teresa Pardo-MorenoHiman Mohamed-MohamedAntonio Rivas-DomínguezVictoria Garcia-MoralesRuben A Garcia-LaraNora Suleiman-MartosBeatriz Bermudez-PulgarinJuan Jose Ramos-RodriguezPublished in: Biomedicines (2023)
Life expectancy has been boosted in recent decades at expenses of increasing the age-associated diseases. Dementia, for its incidence, stands out among the pathologies associated with aging. The exacerbated cognitive deterioration disables people from carrying out their daily lives autonomously and this incidence increases exponentially after 65 years of age. The etiology of dementia is a miscellaneous combination of risk factors that restrain the quality of life of our elderly. In this sense, it has been established that some metabolic pathologies such as obesity and diabetes act as a risk factor for dementia development. In contrast, a high educational level, as well as moderate physical activity, have been shown to be protective factors against cognitive impairment and the development of dementia. In the present study, we have evaluated the metabolic composition of a population between 60-90 years old, mentally healthy and with high academic degrees. After assessing agility in mental state, we have established relationships between their cognitive abilities and their body composition. Our data support that excess body fat is associated with poorer maintenance of cognition, while higher percentages of muscle mass are associated with the best results in the cognitive tests.
Keyphrases
- cognitive impairment
- mild cognitive impairment
- body composition
- risk factors
- physical activity
- type diabetes
- metabolic syndrome
- weight loss
- adipose tissue
- cardiovascular disease
- insulin resistance
- bone mineral density
- magnetic resonance imaging
- resistance training
- body mass index
- computed tomography
- electronic health record
- weight gain
- multiple sclerosis
- white matter
- glycemic control
- high intensity
- medical students
- obese patients