PEGylated SOCS3 Mimetics Encapsulated into PLGA-NPs as Selective Inhibitors of JAK/STAT Pathway in TNBC Cells.

Sara La MannaAlessia CuguddaFlavia Anna MercurioMarilisa LeoneSara FortunaConcetta Di NataleElena LagrecaPaolo Antonio NettiValeria Panzetta Daniela Marasco

Published in: International journal of nanomedicine (2024)

Overall, the data indicated that miniaturization of the SOCS3 protein is a promising therapeutic approach for aberrant dysregulation of JAK/STAT during cancer progression.

Keyphrases

induced apoptosis
papillary thyroid
cell cycle arrest
drug delivery
squamous cell
electronic health record
big data
cell death
endoplasmic reticulum stress
squamous cell carcinoma
protein protein
binding protein
small molecule
artificial intelligence