Risk factors for tuberculosis among close IGRA-negative contacts of persons with infectious tuberculosis in Singapore.

Isabel Tavitian-ExleyWin Mar KyawLim Leo Kang-YangKelly FooIrving Charles BoudvilleJeffery Lawrence CutterDeborah Hee Ling Ng

Published in: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases (2024)

Identifying risk factors could help optimise follow-up strategies and preventive treatment in IGRA-negative individuals. The incidence rate of TB in this group was 150 per 100,000 population, substantially higher than in the community, with a median 92 weeks to develop disease. Findings suggest that follow-up should be extended to 24 months for contacts with these risk factors.

Keyphrases

risk factors
mycobacterium tuberculosis
pulmonary tuberculosis
hiv aids
mental health
emergency department
gestational age
hepatitis c virus
preterm birth
hiv infected