Epstein-Barr Virus-related mucocutaneous ulcer lymphoma associated with Crohn's disease, treated with monoclonal antibody anti-CD30.

Lydiane MordierEstelle TredezClara YzetCaroline DeletteDenis ChatelainDelphine LebonMathurin FumeryJean-Pierre Marolleau

Published in: Clinical case reports (2020)

Epstein-Barr virus-related mucocutaneous ulcer lymphoma is a rare entity promoted by immunosuppression. It is less described in inflammatory bowel diseases, and mostly these are refractory diseases. CD30 acts to Epstein-Barr virus (EBV) local proliferation and thus could be an interesting target. Brentuximab vedotin could become a new helpful tool.

Keyphrases

epstein barr virus
diffuse large b cell lymphoma
monoclonal antibody
hodgkin lymphoma
signaling pathway
nk cells