Gene Expression Signatures of BRCAness and Tumor Inflammation Define Subgroups of Early-Stage Hormone Receptor-Positive Breast Cancer Patients.
Werner SchrothFlorian A BüttnerSiarhei KandabarauReiner HoppePeter Andreas FaschingJörg KumbrinkThomas KirchnerHeather A BrauerYuqi RenDavid HendersonStephen F MaddenGeorg SauerTanja FehmDiethelm WallwienerThomas MürdterMatthias SchwabHiltrud B Brauchnull nullPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
BRCA-related DNA repair deficiency and suppressed tumor immune responses may be clinically relevant predictors of endocrine therapy complementing treatment options in subgroups of hormone-sensitive early breast cancer.