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Nitazene test strips: a laboratory evaluation.

Liam M De VriezeChristophe Pol StoveMarthe M Vandeputte
Published in: Harm reduction journal (2024)
This study provides a better understanding of the potential of NTS for drug checking purposes. Our findings indicate that NTS can theoretically alert to the presence of most nitazene analogues that have emerged on recreational drug markets. However, 'desnitazenes' (lacking the 5-nitro group) may yield false negative results due to low cross-reactivity. Although factors like specificity, lot-to-lot variability, nitazene analogue content in drug samples, solubility, and different testing conditions should be considered, our study results indicate that, at least under the conditions evaluated here (using reference standards and sourced powders), NTS are capable of detecting the presence of a wide range of nitazene analogues. Hence, NTS may alert users of the presence of nitazene analogues in drug samples.
Keyphrases
  • molecular docking
  • adverse drug
  • emergency department
  • molecular dynamics simulations