Genomic discordances and heterogeneous mutational burden, PD-L1 expression and immune infiltrates of non-small cell lung cancer metastasis.
Jianghua WuLuning MaoWanjun LeiWei SunXin YangYanhui ZhangXiaozheng HuangDongmei LinPublished in: Journal of clinical pathology (2024)
The mutational burden, PD-L1 expression and IC infiltrates undergo changes during NSCLC metastasis, which may impact the immunotherapeutic benefits in patients with NSCLC with metastatic progression and should be monitored according to clinical scenarios.