Hepatitis C Treatment Outcomes in Persons With HIV and Decompensated Cirrhosis Using a Collaborative Multidisciplinary HIV-Centered Approach.
Edward R CachayAlvaro MenaLuis Enrique MoranoLaura BenitezIvana MaidaCarmen DE MendozaLucas HillFrancesca TorrianiVincente SorianoW C Mathewsnull nullPublished in: Journal of the International Association of Providers of AIDS Care (2021)
Fifty-four consecutive persons with HIV co-infected with hepatitis C virus (HCV) and liver decompensation were treated with direct-acting antivirals (DAA). The HCV treatment was delivered using a multidisciplinary HIV-coinfection model of care integrating sub-specialty services in 3 countries. Of those treated, 91% (95% confidence interval, 80.1 to 95.9) achieved sustained viral response, and only one person died during treatment. Our study provides evidence that HIV providers achieve excellent outcomes when treating patients with histories of decompensated liver disease, with characteristics similar to those studied using a multidisciplinary HIV-centered approach.
Keyphrases
- hepatitis c virus
- human immunodeficiency virus
- antiretroviral therapy
- hiv positive
- hiv testing
- hiv infected
- hiv aids
- men who have sex with men
- healthcare
- heart failure
- quality improvement
- primary care
- palliative care
- adipose tissue
- ejection fraction
- insulin resistance
- metabolic syndrome
- affordable care act
- weight loss