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miRNA and mRNA Integration Network Construction Reveals Novel Key Regulators in Left-Sided and Right-Sided Colon Adenocarcinoma.

Likun YangLin LiJunhong MaShimin YangChanglin ZouXiangyang Yu
Published in: BioMed research international (2019)
A total of three DEmiRNAs (hsa-miR-224-5p, hsa-miR-155-5p, and hsa-miR-31-5p) and five DEmRNAs (CXCR4, SMAD4, KRAS, FITM2, and PLAGL2) may be involved in the pathogenesis of RSCOAD and LSCOAD which may make a contribution for understanding mechanisms and developing therapeutic strategies for RSCOAD and LSCOAD.
Keyphrases
  • squamous cell carcinoma
  • epithelial mesenchymal transition
  • transcription factor
  • transforming growth factor
  • locally advanced
  • radiation therapy
  • cell migration