Novel Histone Deacetylase 6 Inhibitor Confers Anti-inflammatory Effects and Enhances Gut Barrier Function.
Jae-Young LeeHyun Woo MaJi Hyung KimI Seul ParkMijeong SonKeun Ho RyuJieun ShinSeung Won KimJae Hee CheonPublished in: Gut and liver (2022)
The present study demonstrated that CKD-506 has anti-inflammatory effects on PBMCs and CD4 T cells and improves gut barrier function, suggesting its potential as a small-molecule therapeutic option for IBD.