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Effective treatment of MET exon 14 skipping mutation-positive non-small cell lung cancer using capmatinib following serious maculopapular rash caused by two MET inhibitors: a case report.

Fumihiro KashizakiShunsuke OkazakiNanami TsuchiyaHao ChenHarumi KoizumiKenichi Takahashi
Published in: AME case reports (2024)
exon 14 skipping mutation-positive NSCLC wherein partial response was achieved without severe TRAEs by alternating between two MET inhibitors. If no alternative treatments are available, cautious repeated re-administration of MET inhibitors after resolving serious rashes can be considered a potential approach.
Keyphrases
  • tyrosine kinase
  • small cell lung cancer
  • early onset
  • epidermal growth factor receptor
  • advanced non small cell lung cancer
  • climate change