First-line surgery in prolactinomas: lessons from a long-term follow-up study in a tertiary referral center.
Lukas AndereggenJ FreyR H AndresM M LuediM El-KoussyH R WidmerJ BeckL MarianiR W SeilerE ChristPublished in: Journal of endocrinological investigation (2021)
First-line surgery in patients with microprolactinomas or macroprolactinomas Knosp grade 0 resulted in a good chance of non-dependency on DA therapy. However, in patients with prolactinomas Knosp grade 1, first-line surgery cannot be recommended, as adjuvant DA therapy after surgery is required in the majority of them over the long term.